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Maria Beumont Selected Research

Simeprevir

6/2020Simeprevir, daclatasvir, and sofosbuvir for hepatitis C virus-infected patients: Long-term follow-up results from the open-label, Phase II IMPACT study.
1/2019JNJ-4178 (AL-335, Odalasvir, and Simeprevir) for 6 or 8 Weeks in Hepatitis C Virus-Infected Patients Without Cirrhosis: OMEGA-1.
12/2017Pharmacokinetic Interactions between Simeprevir and Ledipasvir in Treatment-Naive Hepatitis C Virus Genotype 1-Infected Patients without Cirrhosis Treated with a Simeprevir-Sofosbuvir-Ledipasvir Regimen.
1/2017Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study.
5/2015Efficacy and safety of simeprevir with PegIFN/ribavirin in naïve or experienced patients infected with chronic HCV genotype 4.
5/2015Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies.
11/2014Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.
8/2014Fatigue during treatment for hepatitis C virus: results of self-reported fatigue severity in two Phase IIb studies of simeprevir treatment in patients with hepatitis C virus genotype 1 infection.

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Maria Beumont Research Topics

Disease

15Infections
01/2023 - 06/2011
8Chronic Hepatitis C
01/2019 - 02/2011
3Chronic Hepatitis B
01/2023 - 11/2022
3Fibrosis (Cirrhosis)
01/2019 - 10/2012
1Hepatitis B
01/2023
1Portal Hypertension
06/2020
1Liver Diseases (Liver Disease)
06/2020
1Persistent Infection
11/2014
1Fatigue
08/2014
1Insulin Resistance
10/2012
1Hepatitis C
01/2012
1Anemia
06/2011
1Leukopenia
06/2011
1Neutropenia
06/2011

Drug/Important Bio-Agent (IBA)

10Ribavirin (Virazole)FDA LinkGeneric
01/2017 - 02/2011
8SimeprevirIBA
06/2020 - 08/2014
8telaprevirIBA
05/2014 - 02/2011
5Antiviral Agents (Antivirals)IBA
01/2023 - 09/2011
5Protease Inhibitors (Protease Inhibitor)IBA
12/2017 - 01/2013
3Hepatitis B Surface Antigens (HBsAg)FDA Link
01/2023 - 11/2022
3JNJ-56136379IBA
01/2023 - 11/2022
3InterferonsIBA
01/2019 - 01/2013
3peginterferon alfa-2a (Pegasys)FDA Link
09/2011 - 02/2011
2Small Interfering RNA (siRNA)IBA
01/2023 - 11/2022
2Hepatitis B e AntigensIBA
01/2023 - 01/2023
2SofosbuvirIBA
06/2020 - 11/2014
1Tenofovir (Viread)FDA Link
01/2023
1Alanine Transaminase (SGPT)IBA
01/2023
1AntigensIBA
01/2023
1entecavirFDA Link
01/2023
1DNA (Deoxyribonucleic Acid)IBA
01/2023
1daclatasvirIBA
06/2020
1odalasvirIBA
01/2019
1sofosbuvir drug combination ledipasvirIBA
12/2017
1ledipasvirIBA
12/2017
1LDL CholesterolIBA
10/2012
1RNA (Ribonucleic Acid)IBA
09/2011

Therapy/Procedure

7Therapeutics
01/2023 - 06/2011
2Aftercare (After-Treatment)
07/2013 - 10/2012
1Duration of Therapy
06/2020
1Retreatment
06/2011